Genshin 6.0 Sanctifying Elixir: Farm 11+ Guide & Perfect Craft Costs
Buffget
2025/12/17
Sanctifying Elixir lets you craft custom 5-star artifacts with handpicked main stats and up to two sub-stats—perfect for the 6.0 meta. Unlock it after collecting 25 five-star artifacts, then farm via Transmuter (100 progress per Elixir), Natlan troves (5 from tribe rings), BP Lv26 (1), and Pyro Sigils (4 total). Goblets eat up 4 Elixirs each, Sands take 2—prioritize those. And hey, 5.5's QoL update guarantees two substat upgrades by Lv20 on fresh crafts. Game-changer.
Related Guide: Genshin Impact Ultimate Artifacts Pillar Guide
What is Sanctifying Elixir in Genshin Impact 6.0?
Picture this: you're at the Transmuter, picking exact main stats for Sands, Goblet, or Circlet, plus two sub-stats like CRIT Rate, ATK%, or EM. Sanctifying Elixir makes it happen for 5-star artifacts. Dropped in 5.0 (Aug 28, 2024), with that sweet 5.5 QoL bump—two upgrades by Lv20 right out the gate. Unlock through Adventurer's Handbook Ch4 after 25 five-stars. Then extract your junk 5-stars to fuel 6.0's EM/CRIT-heavy Natlan sets. No more praying to the RNG gods.
Unlocking and Using the Artifact Transmuter

Hit 25 five-stars via the Handbook's Embattle quest (5.0 and up), then head to Inventory > Gadgets. Extraction's straightforward: pump +4 or higher 5-stars for points—Lv4-11 (level), Lv12-15 (level+2), Lv16-19 (level+6), Lv20 (30 points). Stack to 100 for one Elixir. Caps at 1 per cycle per version.
Quick tips?
- Boost junk to +4 first.
- Slot 'em in and process.
- Only sacrifice the trash—duh.
Crafting? One per set per version. Simple.
How to Farm Sanctifying Elixirs Efficiently

Pull from Transmuter (1 per cycle), Natlan troves (5 total), BP Lv26 (1), and Pyro Sigils at Lv10/20/30/40 (4 in all). Those tribe rings? Yellow (Echoes), Green (Canopy), Azure (Springs), Crimson (Flower-Feather), Sunset-Blue (Plenty)—each nets one Elixir, so 3-5 easy.
Farm loop:
- Scour tribes for fragments and rings.
- Grind dailies to BP Lv26.
- Hit sigil exchanges.
- Transmuter after reset.
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Related Guide: 6.0 Artifact Farming Routes
Elixir Consumption and Piece-Specific Costs
Break it down:
- Flower: 1 Elixir, fixed HP. Low priority—skip unless desperate.

- Plume: 1, fixed ATK. Yeah, pass.
- Sands: 2, for ATK%/HP%/DEF%/ER%/EM. Craft these early.
- Goblet: 4, Elemental DMG Bonus. Brutal RNG for 6.0's Lunar sets—worth it.
- Circlet: 3, CRIT Rate/DMG/Healing. Save for endgame polish.
Plan ahead: Check inventory Elixirs, list needs (like 4 for Mavuika's Goblet). Goblet and Sands first. Leftovers to Circlet. Full set? 11 Elixirs minimum.
Step-by-Step Guide to Crafting Perfect Artifacts
Spits out a 5-star with your main stat (Sands/Goblet/Circlet), two chosen subs, and post-5.5, two upgrades by Lv20. Boom—four subs total.
Steps:
- Unlock with 25 5-stars.

- Hoard 100+ Elixirs.
- Gadgets > Transmuter.
- Pick set, piece, main (say, EM Sands), subs (CRIT DMG/ATK%).
- Confirm. Level to 20+.
Limits: 1 craft per set per version. That's your perfect right there—main + 2 subs + 2 upgrades.
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Related Guide: Best Natlan Character Builds
Priority Strategies and Comparisons
Goblet (4) > Sands (2) > Circlet (3) > Flower/Plume (1). Why? Tames the worst RNG. Domains? Random Strongbox hell. Elixir? Targeted mains and subs—data shows it's leagues better for meta pieces.
Strategy:
- Eyeball your junk 5-stars.
- Budget 4 Goblets > 2 Sands > 3 Circlets.
- Hold for reset (post-6.0).
Limits bite: 1 extraction/cycle, 1 craft/set/version. (My take: Patience pays—rushed crafts waste Elixirs.)
Natlan 6.0 Full Patch Notes: Link
Common Limits, Mistakes, and Solutions
Watch for: 1 Elixir/cycle/version, 1 craft/set/version. Pitfalls? Wasting on Flower/Plume first. Extracting keepers. Forgetting resets.
Fixes:
- Log cycles in notes.
- Multi-source: Transmuter + 5 troves + 4 sigils + 1 BP = 11+.
- Hit Lv20 before extracting (30 pts).
Ever wonder why newbies burn out here? Overcrafting early pieces—seen it a ton.
FAQ: Sanctifying Elixir Quick Answers
What is Sanctifying Elixir used for?
Crafts 5-star artifacts with custom mains (Sands/Goblet/Circlet), two sub-stats in Transmuter.
How many Elixirs per artifact piece?
Flower/Plume:1; Sands:2; Goblet:4; Circlet:3. Prioritize Goblet/Sands.
Where to get Sanctifying Elixirs in Natlan?
Tribal troves (5 via rings), Pyro Sigils (4), BP Lv26 (1), Transmuter (1/cycle).
Does it guarantee perfect substats?
Post-5.5: two upgrades by Lv20; select two initially.
Unlock requirements?
25 five-stars via Adventurer's Handbook.
Version limits?
1 extraction/craft per set/version; resets post-patch like 6.0.

